Mesotherapy is a minimally invasive procedure where a series of superfine injections of nutrients are delivered into the mesodermal layer of the skin. This infusion of savvy ingredients nourishes and rejuvenates the skin while also stimulating the production of collagen and elastin, both essential for skin's natural elasticity. Treatment time takes approximately 30 minutes and whilst not painful, it can be slightly uncomfortable so an anesthetic cream can be used if skin is a little sensitive. With minimal downtime – a little bruising and swelling may occur but it will be short lived and should settle within 24 hours – skin will become more radiant, hydrated, nourished and firmer with an improved texture. Mesotherapy can instantly improve dull, tired looking skin and superficial wrinkles but can also help to improve sluggish blood circulation, aiding the body to flush out ageing toxins. This treatment can also be used to address pigmentation problems, treat acne scarring and be combined to enhance the effects of other aesthetic treatments. Reborn PLLA hydrogel filler mainly applies mesotherapy. The best way to inject hydrogel is to use mesogun to inject. If there is no mesogun. You can inject it with a hand needle. Its injection depth is 0.9-1.6mm, which is adjusted according to the patient's skin condition and pain.